Publication List

Isamu SHIINA, Ph.D.

1. Catalytic Asymmetric Aldol Reaction of Silyl Enol Ethers with Aldehydes by the Use of Chiral Diamine Coordinated Tin(II) Triflate,
Teruaki MUKAIYAMA, Shu KOBAYASHI, Hiromi UCHIRO, and Isamu SHIINA,
Chemistry Letters, 1990, 129-132.

2. Facile Synthesis of Optically Active anti-a,b-Dihydroxy Ester Derivatives,
Teruaki MUKAIYAMA, Hiromi UCHIRO, Isamu SHIINA, and Shu KOBAYASHI,
Chemistry Letters, 1990, 1019-1022.

3. A Convenient and Versatile Route for the Stereoselective Synthesis of Monosaccharides via Key Chiral Synthons from Achiral Sources,
Teruaki MUKAIYAMA, Isamu SHIINA, and Shu KOBAYASHI,
Chemistry Letters, 1990, 2201-2204.

4. Asymmetric Aldol Reaction between Achiral Silyl Enol Ethers and Achiral Aldehydes by Use of a Chiral Promoter System,
Shu KOBAYASHI, Hiromi UCHIRO, Yuko Fujishita, Isamu SHIINA, and Teruaki MUKAIYAMA,
J. Am. Chem. Soc., 113, 4247-4252 (1991).

5. Highly Enantioselective Synthesis of syn-a,b-Dihydroxy Thioesters by the Asymmetric Aldol Reaction Using a Chiral Tin(II) Lewis Acid,
Teruaki MUKAIYAMA, Isamu SHIINA, and Shu KOBAYASHI,
Chemistry Letters, 1991, 1901-1904.

6. An Efficient Method for the Preparation of Chiral Synthons Starting from Racemic Compounds by way of Asymmetric Synthesis,
Shu KOBAYASHI, Isamu SHIINA, Jun Izumi, and Teruaki MUKAIYAMA,
Chemistry Letters, 1992, 373-376.

7. An Efficient Method for the Preparation of Carboxylic Esters via Mixed Anhydrides by the Promotion of a Catalytic Amount of Lewis Acid,
Teruaki MUKAIYAMA, Isamu SHIINA, and Mitsutomo MIYASHITA,
Chemistry Letters, 1992, 625-628.

8. A New and Efficient Method for the Preparation of S-Phenyl Carbothioates via Mixed Anhydrides Using Active Titanium(IV) Salts,
Teruaki MUKAIYAMA, Mitsutomo MIYASHITA and Isamu SHIINA,
Chemistry Letters, 1992, 1747-1750.

9. The Esterification Reaction between Silyl Derivatives of Carboxylic Acids and Alcohols by the Promotion of a Catalytic Amount of Lewis Acid,
Isamu SHIINA and Teruaki MUKAIYAMA,
Chemistry Letters, 1992, 2319-2320.

10. Catalytic Asymmetric Aldol-type Reaction Using a Chiral Tin(II) Lewis Acid,
Shu KOBAYASHI, Hiromi UCHIRO, Isamu SHIINA, and Teruaki MUKAIYAMA,
Tetrahedron, 49, 1761-1772 (1993).

11. A New and Efficient Esterification Reaction via Mixed Anhydrides by the Promotion of a Catalytic Amount of Lewis Acid,
Mitsutomo MIYASHITA, Isamu SHIINA, So MIYOSHI, and Teruaki MUKAIYAMA,
Bull. Chem. Soc. Jpn., 66, 1516-1527 (1993).

12. Enantioselective Synthesis of the a-Hydroxy-a-methyl-b-hydroxy Units via Asymmetric Aldol Reaction,
Teruaki MUKAIYAMA, Isamu SHIINA, Jun IZUMI, and Shu KOBAYASHI,
Heterocycles, 35, 719-724 (1993).

13. Facile Synthesis of Lactones from Silyl w-Siloxycarboxylates Using p-Trifluoromethylbenzoic Anhydride and a Catalytic Amount of Active Lewis Acid,
Teruaki MUKAIYAMA, Jun IZUMI, Mitsutomo MIYASHITA, and Isamu SHIINA,
Chemistry Letters, 1993, 907-910.

14. Facile Syntheses of Amino-6-deoxyaldohexoses from Simple Achiral Starting Materials,
Teruaki MUKAIYAMA, Hideki ANAN, Isamu SHIINA, and Shu KOBAYASHI,
Bull. Soc. Chim. Fr., 130, 388-394 (1993).

15. A Convenient Synthesis of Carboxanilides from Silyl Carboxylates and Weakly Nucleophilic Anilines Using p-Trifluoromethylbenzoic Anhydride and a Catalytic Amount of Active Titanium(IV) Salt,
Mitsutomo MIYASHITA, Isamu SHIINA, and Teruaki MUKAIYAMA,
Chemistry Letters, 1993, 1053-1054.

16. An Effective Method for Acylation of Weakly Nucleophilic Anilines with Silyl Carboxylates via Mixed Anhydrides,
Mitsutomo MIYASHITA, Isamu SHIINA, and Teruaki MUKAIYAMA,
Bull. Chem. Soc. Jpn., 67, 210-215 (1994).

17. A Useful Method for the Preparation of Carboxylic Esters from Free Carboxylic Acids and Alcohols,
Isamu SHIINA, So MIYOSHI, Mitsutomo MIYASHITA, and Teruaki MUKAIYAMA,
Chemistry Letters, 1994, 515-518.

18. A Novel Method for the Preparation of Macrolides from w-Hydroxycarboxylic Acids,
Isamu SHIINA and Teruaki MUKAIYAMA,
Chemistry Letters, 1994, 677-680.

19. Diastereo- and Enantioselective Synthesis of syn- and anti-1,2-Diol Units by Asymmetric Aldol Reactions,
Teruaki MUKAIYAMA, Isamu SHIINA, Hiromi UCHIRO, and Shu KOBAYASHI,
Bull. Chem. Soc. Jpn., 67, 1708-1716 (1994).

20. An Effective Method for Formylation of Weakly Nucleophilic Anilines and Indole,
Isamu SHIINA, Mitsutomo MIYASHITA, Masashi NAGAI, and Teruaki MUKAIYAMA,
Heterocycles, 40, 141-148 (1995).

21. The Catalytic Diels-Alder Reaction Using Combined Catalyst System of Diphenyltin Sulfide or Lawesson's Reagent and Silver Perchlorate,
Teruaki MUKAIYAMA, Kimitoshi WATANABE, and Isamu SHIINA,
Chemistry Letters, 1995, 1-2, 332.

22. An Efficient Esterification Reaction between Free Carboxylic Acids and Alcohols by the Combined Use of Octamethylcyclotetrasiloxane and a Catalytic Amount of Titanium(IV) chloride tris(trifluoromethanesulfonate),
Jun IZUMI, Isamu SHIINA, and Teruaki MUKAIYAMA,
Chemistry Letters, 1995, 141-142.

23. A Novel Approach to the Synthesis of Taxol. A Synthesis of Optically Active 3,7-Dibenzyloxy-4,8-di-t-butyldimethylsiloxy-5,5-dimethyl-6-p-methoxybenzyloxy-2-octanone by Way of Stereoselective Aldol Reactions,
Teruaki MUKAIYAMA, Isamu SHIINA, Kaku SAKATA, Takayuki EMURA, Keitarou SETO, and Masahiro SAITOH,
Chemistry Letters, 1995, 179-180.

24. An Asymmetric Synthesis of Fully Functionalized B Ring System of Taxol,
Isamu SHIINA, Kouichi UOTO, Nobuaki MORI, Tomomi KOSUGI, and Teruaki MUKAIYAMA,
Chemistry Letters, 1995, 181-182.

25. Synthesis of AB Ring Model System of Taxol via Allylation of 8-Membered Ring Compound and Intramolecular Aldol Condensation,
Teruaki MUKAIYAMA, Isamu SHIINA, Kaname KIMURA, Yuji AKIYAMA, and Hayato IWADARE,
Chemistry Letters, 1995, 229-230.

26. An Asymmetric Synthesis of the Fully Functionalized AB Ring System of 12-Demethyltaxol via Successive Stereoselective Allylation and Intramolecular Aldol Reactions,
Isamu SHIINA, Hayato IWADARE, Masahiro SAITOH, Naoto OHKAWA, Toshihiro NISHIMURA, and Teruaki MUKAIYAMA,
Chemistry Letters, 1995, 781-782.

27. New and Effective Synthesis of 7-Triethylsilylbaccatin III from 7b,13a-Bistriethylsiloxy-1b,2a,10b-trihydroxy-9-oxo-4(20),11-taxadiene,
Isamu SHIINA, Masahiro SAITOH, Koji NISHIMURA, Katsuyuki SAITOH, and Teruaki MUKAIYAMA,
Chemistry Letters, 1996, 223-224.

28. An Asymmetric Synthesis of the BC Ring System of 8-Epitaxoids by Way of Intramolecular Aldol and Successive Stereoselective Methylation Reactions,
Teruaki MUKAIYAMA, Isamu SHIINA, Hayato IWADARE, Masahiro SAITOH, Koji NISHIMURA, Toshihiro NISHIMURA, Naoto OHKAWA, Hiroki SAKOH, and Katsuyuki SAITOH,
Chemistry Letters, 1996, 483-484.

29. New and Efficient Method for the Preparation of Medium-sized Lactones from the Corresponding w-Hydroxycarboxylic Acids,
Teruaki MUKAIYAMA, Jun IZUMI, and Isamu SHIINA,
Chemistry Letters, 1997, 187-188.

30. An Asymmetric Synthesis of the ABC Ring System of 8-Demethyltaxoids from Optically Active 8-Membered Ring Compound via Intramolecular Aldol and Pinacol Coupling Reactions,
Isamu SHIINA, Toshihiro NISHIMURA, Naoto OHKAWA, Hiroki SAKOH, Koji NISHIMURA, Katsuyuki SAITOH, and Teruaki MUKAIYAMA,
Chemistry Letters, 1997, 419-420.

31. Asymmetric Total Synthesis of Taxol,
Teruaki MUKAIYAMA, Isamu SHIINA, Hayato IWADARE, Hiroki SAKOH, Yu-ichirou TANI, Masatoshi HASEGAWA, and Katsuyuki SAITOH,
Proceedings of the Japan Academy, 73B, 95-100 (1997).

32. Stereocontrolled Synthesis of the BC Ring System of Taxol,
Isamu SHIINA, Hayato IWADARE, Hiroki SAKOH, Yu-ichirou TANI, Masatoshi HASEGAWA, Katsuyuki SAITOH, and Teruaki MUKAIYAMA,
Chemistry Letters, 1997, 1139-1140.

33. A New Method for the Synthesis of Baccatin III,
Isamu SHIINA, Hayato IWADARE, Hiroki SAKOH, Masatoshi HASEGAWA, Yu-ichirou TANI, and Teruaki MUKAIYAMA,
Chemistry Letters, 1998, 1-2.

34. Total Asymmetric Synthesis of Taxol by Dehydration Condensation between 7-TES Baccatin III and Protected N-Benzoylphenylisoserines Prepared by Enantioselective Aldol Reaction,
Isamu SHIINA, Katsuyuki SAITOH, Isabelle Fr残hard-ORTUNO, and Teruaki MUKAIYAMA,
Chemistry Letters, 1998, 3-4.

35. Synthetic Studies on Antitumor Agent Taxol,
Isamu SHIINA,
SUT Bulletin, 1998, 34-39.

36. O,O'-Di(2-pyridyl) Thiocarbonate as an Efficient Reagent for the Preparation of Carboxylic Esters from Highly Hindered Alcohols,
Katsuyuki SAITOH, Isamu SHIINA, and Teruaki MUKAIYAMA,
Chemistry Letters, 1998, 679-680.

37. Determination of Relative and Absolute Stereochemistry of Cephalosporolide D and its Enantioselective Total Synthesis,
Isamu SHIINA, Yoshio FUKUDA, Toshihiro ISHII, Hidehiko FUJISAWA, and Teruaki MUKAIYAMA,
Chemistry Letters, 1998, 831-832.

38. Efficient Method for Pinacol Coupling of Aromatic and Aliphatic Ketones by Using Titanium(II) Chloride and Zinc in the Presence of Pivalonitrile,
Teruaki MUKAIYAMA, Akifumi KAGAYAMA, and Isamu SHIINA,
Chemistry Letters, 1998, 1107-1108.

39. Asymmetric Total Synthesis of Taxol,
Teruaki MUKAIYAMA, Isamu SHIINA, Hayato IWADARE, Masahiro SAITOH, Toshihiro NISHIMURA, Naoto OHKAWA, Hiroki SAKOH, Koji NISHIMURA, Yu-ichirou TANI, Masatoshi HASEGAWA, Koji YAMADA, and Katsuyuki SAITOH,
Chemistry - a European Journal, 5, 121-161 (1999). [Cover Article]

40. Diethylaluminum Ethoxide Mediated Stereoselective Diels-Alder Reaction of a,b-unsaturated Ketones and Acetoxy-1,3-butadienes as Diene Components,
Jun SHIBATA, Isamu SHIINA, and Teruaki MUKAIYAMA,
Chemistry Letters, 1999, 313-314.

41. Synthesis of 18-Demethyltaxoid via Stereoselective Allylation and Intramolecular Aldol Condensation Reactions,
Hayato IWADARE, Hiroki SAKOH, Hidehiro ARAI, Isamu SHIINA, and Teruaki MUKAIYAMA,
Chemistry Letters, 1999, 817-818.

42. Diethylaluminum Ethoxide Mediated Crossed Aldol Reaction of Enol Esters with Carbonyl Compounds,
Teruaki MUKAIYAMA, Jun SHIBATA, Tadashi SHIMAMURA, and Isamu SHIINA,
Chemistry Letters, 1999, 951-952.

43. An Effective Method for the Preparation of Optically Active Polyoxy 8-Membered Ring Enone Corresponding to B Ring of Taxol,
Isamu SHIINA, Jun SHIBATA, Yumiko IMAI, Ryoutarou IBUKA, Hidehiko FUJISAWA, Iwao HACHIYA, and Teruaki MUKAIYAMA,
Chemistry Letters, 1999, 1145-1146.

44. Diastereoselective Aldol Reaction of a-Bromo Ketones with Aliphatic Aldehydes by Using Titanium(II) Chloride and Copper,
Teruaki MUKAIYAMA, Akifumi KAGAYAMA, Koji IGARASHI, and Isamu SHIINA,
Chemistry Letters, 1999, 1157-1158.

45. Synthesis of Biologically Active Natural and Unnatural Organic Compounds,
Isamu SHIINA,
SUT Bulletin, 2000, 38.

46. A Direct and Selective Syntheses of a,a-Dichloro- and a-Chloro-ethyl Ketones by the Reaction of Alkyl Carboxylates with 1,1-Dichloroethyllithium,
Isamu SHIINA, Yumiko IMAI, Akifumi KAGAYAMA, and Teruaki MUKAIYAMA,
Chemistry Letters, 2000, 190-191.

47. Stereoselective Total Synthesis of Cephalosporolide D,
Isamu SHIINA, Hidehiko FUJISAWA, Toshihiro ISHII, and Yoshio FUKUDA,
Heterocycles, 52, 1105-1123 (2000).

48. Asymmetric Total Synthesis of Taxol,
Teruaki MUKAIYAMA and Isamu SHIINA,
Gendai Kagaku Zohkan, 36, 144-157 (2000).

49. Total Synthesis of Natural Products,
Teruaki MUKAIYAMA and Isamu SHIINA,
Kikan Kagaku Sosetsu, 45, 227-230 (2000).

50. A New Method for the Synthesis of Unsymmetrical Bis-Aldols by the Samarium(II) Iodide-Mediated Aldol Reaction of Aldehydes with Aryl or Alkyl Oxiranyl Ketones,
Teruaki MUKAIYAMA, Hidehiro ARAI, and Isamu SHIINA,
Chemistry Letters, 2000, 580-581.

51. A Facile Synthesis of Carboxamides by Dehydration Condensation between Free Carboxylic Acids and Amines Using O,O'-Di(2-pyridyl) Thiocarbonate as a Coupling Reagent,
Isamu SHIINA, Katsuyuki SAITOH, Masakazu NAKANO, Yoshihito SUENAGA, and Teruaki MUKAIYAMA,
Collection of Czechoslovak Chemical Communications, 65, 621-630 (2000).

52. A Direct and Selective Syntheses of a,a-Dichloroethyl Ketones or Its Ethyl Trimethylsilyl Mixed Acetals by the Reactions of Methoxymethyl or Ethyl Carboxylates with 1,1-Dichloroethyllithium in the Presence of Chlorotrimethylsilane,
Isamu SHIINA, Yumiko IMAI, Masahiko SUZUKI, Manabu YANAGISAWA, and Teruaki MUKAIYAMA,
Chemistry Letters, 2000, 1062-1063.

53. Diastereoselective Aldol and Reformatsky Reactions of a-Halo Carbonyl Compounds and Aldehydes Mediated by Titanium(II) Chloride,
Akifumi KAGAYAMA, Koji IGARASHI, Isamu SHIINA, and Teruaki MUKAIYAMA,
Bull. Chem. Soc. Jpn., 73, 2579-2585 (2000).

54. A Convenient Method for the Preparations of Carboxamides and Peptides by Using Di(2-pyridyl) Carbonate and O,O'-di(2-pyridyl) Thiocarbonate as Dehydrating Reagents,
Isamu SHIINA, Yoshihito SUENAGA, Masakazu NAKANO, and Teruaki MUKAIYAMA,
Bull. Chem. Soc. Jpn., 73, 2811-2818 (2000).

55. An Effective Method for the Preparation of Chiral Polyoxy Enone Corresponding to the B Ring of Taxol,
Isamu SHIINA, Jun SHIBATA, Ryotaro IBUKA, Yumiko IMAI, and Teruaki MUKAIYAMA,
Bull. Chem. Soc. Jpn., 74, 113-122 (2001).

56. A Convenient Method for the Preparation of Unsymmetrical Bis-Aldols by Way of Sequential Two Aldol Reactions,
Hidehiro ARAI, Isamu SHIINA, and Teruaki MUKAIYAMA,
Chemistry Letters, 2001, 118-119.

57. Total Synthesis of Natural Compound Using Asymmetric Aldol Reaction (A Review of Chemistry in 2001),
Ryoutarou IBUKA and Isamu SHIINA,
Chemistry, 56 (7), 59-60 (2001).

58. (S)-1-Methyl-2-(piperidinomethyl)pyrrolidine,
Isamu SHIINA and Teruaki MUKAIYAMA,
Electronic Encyclopedia of Reagents for Organic Synthesis, 3, 1-19 (2001).

59. Enantioselective Synthesis of b-Hydroxy-a-methyl-a-methylthio Esters as Precursors of anti-vic-Hydroxymethyl Units,
Isamu SHIINA and Ryoutarou IBUKA,
Tetrahedron Letters, 42, 6303-6306 (2001).

60. Enantioselective Alkylation of Aldehydes with Diethylzinc Using a New Catalyst System, ((R)-Thiolan-2-yl)diphenylmethanol and Metal Alkoxides,
Isamu SHIINA, Katsuhiko KONISHI, and Yu-suke KURAMOTO,
Chemistry Letters, 2002, 164-165.

61. A New Condensation Reaction for the Synthesis of Carboxylic Esters from Nearly Equimolar Amounts of Carboxylic Acids and Alcohols Using 2-Methyl-6-nitrobenzoic Anhydride,
Isamu SHIINA, Ryoutarou IBUKA, and Mari KUBOTA,
Chemistry Letters, 2002, 286-287.

62. [1,3] Sigmatropic Rearrangement of Ketene Silyl Acetals Derived from Benzyl a-Substituted Propanoates,
Isamu SHIINA and Hiroshi NAGASUE,
Tetrahedron Letters, 43, 5837-5840 (2002).

63. The Catalytic Friedel-Crafts Alkylation Reaction of Aromatic Compounds with Benzyl or Allyl Silyl Ethers Using Cl2Si(OTf)2 or Hf(OTf)4,
Isamu SHIINA and Masahiko SUZUKI,
Tetrahedron Letters, 43, 6391-6394 (2002).

64. A Convenient Method for the Synthesis of 4,4-diarylbut-1-enes via the Successive Allylation of Aromatic Aldehydes and the Friedel-Crafts Alkylation Reaction of Anisole with the Intermediary Benzyl Silyl Ethers Using HfCl4 or Cl2Si(OTf)2,
Isamu SHIINA, Masahiko SUZUKI, and Kazutoshi YOKOYAMA,
Tetrahedron Letters, 43, 6395-6398 (2002).

65. A Novel and Efficient Macrolactonization of w-Hydroxycarboxylic Acids Using 2-Methyl-6-nitrobenzoic Anhydride (MNBA),
Isamu SHIINA, Mari KUBOTA, and Ryoutarou IBUKA,
Tetrahedron Letters, 43, 7535-7539 (2002).

66. A New Method for the Synthesis of Carboxamides and Peptides Using 1,1ﾕ-Carbonyldioxydi[2(1H)-pyridone] (CDOP) in the Absence of Basic Promoters,
Isamu SHIINA and Yo-ichi KAWAKITA,
Tetrahedron Letters, 44, 1951-1955 (2003).

67. Reaction Modes of Oxidative Dimerization of Epoxycyclohexenols,
Mitsuru SHOJI, Satoshi KISHIDA, Yusuke KODERA, Isamu SHIINA, Hideaki KAKEYA, Hiroyuki OSADA, and Yujiro HAYASHI,
Tetrahedron Letters, 44, 7205-7207 (2003).

68. Asymmetric Total Synthesis of Octalactin B Using a New and Rapid Lactonization,
Isamu SHIINA, Hiromi OSHIUMI, Minako HASHIZUME, Yu-suke YAMAI, and Ryoutarou IBUKA,
Tetrahedron Letters, 45, 543-547 (2004).

69. Short-Step Synthesis of Tamoxifen and Its Derivatives via the Three-component Coupling Reaction and Migration of the Double Bond,
Isamu SHIINA, Masahiko SUZUKI, and Kazutoshi YOKOYAMA,
Tetrahedron Letters, 45, 965-967 (2004).

70. An Effective Method for the Synthesis of Carboxylic Esters and Lactones Using Substituted Benzoic Anhydrides with Lewis Acid Catalysts,
Isamu SHIINA,
Tetrahedron, 60, 1587-1599 (2004).

71. Different Reaction Modes for the Oxidative Dimerization of Epoxyquinols and Epoxyquinones. Importance of Intermolecular Hydrogen-Bonding,
Mitsuru SHOJI, Hiroki IMAI, Isamu SHIINA, Hideaki KAKEYA, Hiroyuki OSADA, and Yujiro HAYASHI,
J. Org. Chem., 69, 1548-1556 (2004).

72. An Effective Use of Benzoic Anhydride and Its Derivatives for the Synthesis of Carboxylic Esters and Lactones: A Powerful and Convenient Mixed Anhydride Method Promoted by Basic Catalysts,
Isamu SHIINA, Mari KUBOTA, Hiromi OSHIUMI, and Minako HASHIZUME,
J. Org. Chem., 69, 1822-1830 (2004).

73. The Effective Use of Substituted Benzoic Anhydrides for the Synthesis of Carboxamides,
Isamu SHIINA and Yo-ichi Kawakita,
Tetrahedron, 60, 4729-4733 (2004).

74. Taxol derivatives are selective inhibitors of DNA polymerase a,
Masahiko OSHIGE, Mika TAKENOUCHI, Yasutaro KATO, Sinji KAMISUKI, Toshifumi TAKEUCHI, Kouji KURAMOCHI, Isamu SHIINA, Yoshihito SUENAGA, Yo-ichi KAWAKITA, Kazufumi KURODA, Noriyuki SATO, Susumu KOBAYASHI, Fumio SUGAWARA, and Kengo SAKAGUCHI,
Bioorganic & Medicinal Chemistry, 12, 2597-2601 (2004).

75. Tin-promoted Aldol Reactions and Their Application to Total Syntheses of Natural Products,
Isamu SHIINA,
Modern Aldol Reactions Vol 2, Wiley-VCH, 105-165 (2004).

76. Reductive Coupling Reaction of Carbonyl Compounds Using Low-Valent Metallic Species,
Isamu SHIINA,
The Fifth Series of Experimental Chemistry, Vol. 18 (Synthesis of Organic Compounds VI), Maruzen, 426-436 (2004).

77. An Effective Use of Benzoic Anhydride and Its Derivatives for the Synthesis of Carboxylic Esters and Lactones ﾑ Powerful and Convenient Mixed Anhydride Methods Promoted by Lewis Acids or Basic Catalysts (Account),
Isamu SHIINA,
J. Synth. Org. Chem. Jpn., 63, 2-17 (2005).

78. Total Synthesis of Buergerinin F via Effective Construction of the Asymmetric Quaternary Carbons Using Enantioselective Aldol Reaction,
Isamu SHIINA, Yo-ichi KAWAKITA, Ryoutarou IBUKA, Kazutoshi YOKOYAMA, and Yu-suke YAMAI,
Chemical Communications, 2005, 4062-4064.

79. Enantioselective Synthesis of the Optically Active a-Methylene-b-hydroxy Esters, Equivalent Compounds to Morita-Baylis-Hillman Adducts, Using Successive Asymmetric Aldol Reaction and Oxidative Deselenization,
Isamu SHIINA, Yu-suke YAMAI, and Takahisa SHIMAZAKI,
J. Org. Chem., 70, 8103-8106 (2005).

Abstracted by Prof. Douglass F. Taber in Org. Chem. Highlights 2006, July 17.
"Catalytic Enantioselective Homologation of Aldehydes to Alcohols and Amines"

80. Enantioselective Total Synthesis of Octalactin A Using Asymmetric Aldol Reactions and a Rapid Lactonization to Form a Medium-Sized Ring,
Isamu SHIINA, Minako HASHIZUME, Yu-suke YAMAI, Hiromi OSHIUMI, Takahisa SHIMAZAKI, Yu-ji TAKASUNA, and Ryoutarou IBUKA,
Chemistry - a European Journal, 11, 6601-6608 (2005).

81. The Direct, Enantioselective, One-pot, Three-component, Cross-Mannich Reaction of Aldehydes: The Reason for the Higher Reactivity of Aldimine Versus Aldehyde in Proline-Mediated Mannich and Aldol Reactions,
Yujiro Hayashi, Tatsuya URUSHIMA, Mitsuru SHOJI, Tadafumi UCHIMARU, and Isamu SHIINA,
Advanced Synthesis & Catalysis, 347, 1595-1604 (2005).

82. Enantio- and Diastereo-selective Total Synthesis of EI-1941-1, -2 and -3, Inhibitors of Interleukin-1b Converting Enzyme and Biological Properties of Their Derivatives,
Mitsuru SHOJI, Takao UNO, Hideaki KAKEYA, Rie ONOSE, Isamu SHIINA, Hiroyuki OSADA, and Yujiro HAYASHI
J. Org. Chem., 70, 9905-9915 (2005).

83. New Methods for the Preparation of Advanced Organic Materials,
Isamu SHIINA,
Science Forum, 2006, 26-27.

84. Short-step Synthesis of Droloxifene via the Three-component Coupling Reaction among Aromatic Aldehyde, Cinnamyltrimethylsilane, and b-Chlorophenetole,
Yoshiyuki SANO and Isamu SHIINA,
Tetrahedron Letters, 47, 1631-1635 (2006).

85. Computational Study on the Reaction Mechanism of the Key Thermal [4+4] Cycloaddition Reaction in the Biosynthesis of Epoxytwinol A,
Isamu SHIINA, Tadafumi UCHIMARU, Mitsuru SHOJI, Hideaki KAKEYA, Hiroyuki OSADA, and Yujiro HAYASHI,
Organic Letters, 8, 1041-1044 (2006).

86. Synthesis of (9E)-Isoambrettolide, a Macrocyclic Musk Compound, Using the Effective Lactonization Promoted by Symmetric Benzoic Anhydrides with Basic Catalysts,
Isamu SHIINA and Minako HASHIZUME,
Tetrahedron, 62, 7934-7939 (2006).

87. 1-Methoxy-2-methylseleno-1-(trimethylsiloxy)propene,
Isamu SHIINA,
Electronic Encyclopedia of Reagents for Organic Synthesis, 8, 1-12 (2006).

88. Asymmetric Synthesis of 8- or 9-Membered Ring Natural Compounds Using a Rapid Lactonization to Form a Medium-sized Framework,
Isamu SHIINA,
J. Mex. Chem. Soc., 50, Special Issue 1, 262 (2006).

89. Novel Tamoxifen Derivatives Induced Mitochondria-Involved Apoptosis in Non-Oestrogen Receptor Cell,
Yukitoshi NAGAHARA, Isamu SHIINA, Takahisa SHINOMIYA, Masato TANAKA, and Masahiko IKEKITA,
FEBS Journal, 273, Special Issue 1, 113 (2006).

90. Facile Methods for the Preparation of Carboxylic Esters, Carboxamides and Lactones,
Isamu SHIINA,
Chemical Engineering, 51, 702-706 (2006).

91. The First Total Synthesis of (-) and (+)-2-Hydroxy-24-oxooctacosanolide Using an Effective Lactonization,
Isamu SHIINA, Takaaki KIKUCHI, and Akane SASAKI,
Organic Letters, 8, 4955-4958 (2006).

Abstracted by Prof. Douglass F. Taber in Org. Chem. Highlights 2007, April 16.
"Stereocontrolled Natural Product Synthesis: Cyclic Ethers and Macrolides"

92. Stereoselective Total Synthesis of the Proposed Structure of 2-Epibotcinolide,
Isamu SHIINA, Yu-ji TAKASUNA, Ryo-suke SUZUKI, Hiromi OSHIUMI, Yuri KOMIYAMA, Seiichi HITOMI, and Hiroki FUKUI,
Organic Letters, 8, 5279-5282 (2006).

93. An Expeditious Synthesis of Lasofoxifene and Nafoxidine via the Novel Three-component Coupling Reaction,
Yoshiyuki SANO, Kenya NAKATA, Takafumi OTOYAMA, Sei UMEDA, and Isamu SHIINA,
Chemistry Letters, 36, 40-41 (2007).

94. Total Synthesis of Natural 8- and 9-Membered Lactones: Recent Advancements in Medium-Sized Ring Formation,
Isamu SHIINA,
Chemical Reviews, 107, 239-273 (2007). [Cover Feature Article]

95. Synthesis of the New pseudo-Symmetrical Tamoxifen Derivatives and Their Anti-tumor Activity,
Isamu SHIINA, Yoshiyuki SANO, Kenya NAKATA, Takaaki KIKUCHI, Akane SASAKI, Masahiko IKEKITA, and Yoshimune HASOME,
Bioorganic & Medicinal Chemistry Letters, 17, 2421-2424 (2007).

96. Synthesis of Lactones Using Substituted Benzoic Anhydride as a Coupling Reagent,
Isamu SHIINA, Hiroki FUKUI, and Akane SASAKI,
Nature Protocols, 2, 2312-2317 (2007).

97. The First Asymmetric Esterification of Free Carboxylic Acids with Racemic Alcohols Using Benzoic Anhydrides and Tetramisole Derivatives: An Application to the Kinetic Resolution of Secondary Benzylic Alcohols,
Isamu SHIINA and Kenya NAKATA,
Tetrahedron Letters, 48, 8314-8317 (2007). [Cover Feature Article]

98. An Expeditious Synthesis of Tamoxifen, A Representative SERM (Selective Estrogen Receptor Modulator), via the Three-Component Coupling Reaction among Aromatic Aldehyde, Cinnamyltrimethylsilane and b-Chlorophenetole,
Isamu SHIINA, Yoshiyuki SANO, Kenya NAKATA, Masahiko SUZUKI, Toshikazu YOKOYAMA, Akane SASAKI, Tomoko ORIKASA, Tomomi MIYAMOTO, Masahiko IKEKITA, Yukitoshi NAGAHARA, and Yoshimune HASOME,
Bioorganic & Medicinal Chemistry, 15, 7599-7617 (2007).

[Most Accessed Article] [Highlighted in ScienceDirect, October to December 2007, http://top25.sciencedirect.com/subject/medicine-and-dentistry/17/journal/bioorganic-medicinal-chemistry/09680896/archive/14/]

99. 4-(Dimethylamino)pyridine N-oxide (DMAPO): an Effective Nucleophilic Catalyst in the Peptide Coupling Reaction with 2-Methyl-6-nitrobenzoic Anhydride,
Isamu SHIINA, Hisaya USHIYAMA, Yo-ko YAMADA, Yo-ichi KAWAKITA, and Kenya NAKATA,
Chemistry - an Asian Journal, 3, 454-461 (2008).

100. Total Synthesis of 2-Hydroxytetracosanolide and 2-Hydroxy-24-oxooctacosanolide Using an Effective Lactonization,
Isamu SHIINA, Akane SASAKI, Takaaki KIKUCHI, and Hiroki FUKUI,
Chemistry - an Asian Journal, 3, 462-472 (2008).

101. Estrogen Receptor-Independent Apoptosis by a Novel Tamoxifen Derivative, Ridaifen-B,
Yukitoshi NAGAHARA, Isamu SHIINA, Kenya NAKATA, Tomomi MIYAMOTO, and Masahiko IKEKITA,
FEBS Journal, 275, Special Issue 1, 326 (2008).

102. Synthesis and Pharmacological Evaluation of the Novel pseudo-Symmetrical Tamoxifen Derivatives as Anti-tumor Agents,
Isamu SHIINA, Yoshiyuki SANO, Kenya NAKATA, Takaaki KIKUCHI, Akane SASAKI, Masahiko IKEKITA, Yukitoshi NAGAHARA, Yoshimune HASOME, Takao YAMORI, and Kanami YAMAZAKI,
Biochemical Pharmacology, 75, 1014-1026 (2008).

103. Induction of Mitochondria-Involved Apoptosis in Estrogen Receptor Negative Cells by a Novel Tamoxifen Derivative, Ridaifen B,
Yukitoshi NAGAHARA, Isamu SHIINA, Kenya NAKATA, Akane SASAKI, Tomomi MIYAMOTO, and Masahiko IKEKITA,
Cancer Science, 99, 608-614 (2008).

104. Sn(II) and Sn(IV) Lewis Acids,
Isamu SHIINA and Hiroki FUKUI,
New Acid Catalysis for Modern Organic Chemistry, Wiley-VCH, 517-550 (2008).

105. 2-Methyl-6-nitrobenzoic Anhydride (MNBA),
Isamu SHIINA,
Electronic Encyclopedia of Reagents for Organic Synthesis, 10, 1-30 (2008).

106. Asymmetric Total Synthesis of Botcinins C, D, and F,
Hiroki FUKUI and Isamu SHIINA,
Organic Letters, 10, 3153-3156 (2008).

Abstracted by Prof. Douglass F. Taber in Org. Chem. Highlights 2009, April 20.
"C-O Ring Natural Products"

107. Asymmetric Total Synthesis of Botcinic Acid and Its Derivatives: Synthetic Revision of the Structure of Botcinolides,
Hiroki FUKUI, Seiichi HITOMI, Ryo-suke SUZUKI, Tatsuhiko IKEDA, Yuma UMEZAKI, Keisuke TSUJI, and Isamu SHIINA,
Tetrahedron Letters, 49, 6514-6517 (2008). [Cover Feature Article]

108. 2,6-Dimethyl-4-nitrobenzoic Anhydride (DMNBA): an Effective Coupling Reagent for the Synthesis of Carboxylic Esters and Lactones,
Isamu SHIINA and Ryo MIYAO,
Heterocycles, 76, 1313-1328 (2008).

109. Kinetic Resolution of Racemic Carboxylic Acids Using Achiral Alcohols by the Promotion of Benzoic Anhydrides and Tetramisole Derivatives: Production of Chiral Nonsteroidal Anti-Inflammatory Drugs and Their Esters,
Isamu SHIINA, Kenya NAKATA, and Yu-suke ONDA,
European Journal of Organic Chemistry, 2008, 5887-5890.

[Most Accessed Article]

110. 2,2-Disubstituted Propionic Anhydrides: Effective Coupling Reagents for the Kinetic Resolution of Secondary Benzylic Alcohols Using BTM,
Isamu SHIINA, Kenya NAKATA, Masuhiro SUGIMOTO, Yu-suke ONDA, Takashi IIZUMI, and Keisuke ONO,
Heterocycles, 77, 801-810 (2009).

111. Chemistry and Structural Determination of Botcinolides, Botcinins, and Botcinic Acids,
Isamu SHIINA and Hiroki FUKUI,
Chemical Communications, 2009, 385-400. [Feature Article]

112. Total Synthesis and the Confirmation of the Revised Structures of Botcinins A and B,
Hiroki FUKUI, Keisuke TSUJI, Yuma UMEZAKI, and Isamu SHIINA,
Heterocycles, 79, 403-410 (2009).

113. (-)-2-Hydroxy-24-oxooctacosanolide,
Isamu SHIINA,
Total Synthesis of Natural Products 2000-2008, Kagaku Doujin, 92 (2009).

114. (-)-Octalactin A,
Isamu SHIINA,
Total Synthesis of Natural Products 2000-2008, Kagaku Doujin, 161-162 (2009).

115. Total Synthesis of Botcinolides and Botcinins; Determination of the Structure of Natural Products Isolated from Botrytis cinerea (Account),
Hiroki FUKUI and Isamu SHIINA,
J. Synth. Org. Chem. Jpn., 67, 628-642 (2009).

116. Enantioselective Aldol Reaction of Tetrasubstituted Ketene Silyl Acetals with Achiral Aldehydes for the Construction of Asymmetric Tertiary Alcohols: An Application for the Divergent Total Syntheses of Buergerinins F and G,
Isamu SHIINA, Takashi IIZUMI, Yu-Suke YAMAI, Yo-Ichi KAWAKITA, Kazutoshi YOKOYAMA, Yo-Ko YAMADA,
Synthesis, 2009, 2915-2926. [Special Issue of Modern Natural Products Synthesis]

117. "Aromatic Acid Anhydrides" - Versatile and Useful Coupling Reagents for the synthesis of Carboxylic Esters, Lactones, Peptides, and Optically Active Alcohols and Carboxylic Acids,
Isamu SHIINA,
TCI MAIL (Contribution as a Research Article), 144 (10), 2-16 (2009).

118. Evaluation of the Efficiency of the Macrolactonization Using MNBA in the Synthesis of Erythromycin A Aglycon,
Isamu SHIINA, Takashi KATOH, Shunsuke NAGAI, and Minako HASHIZUME,
The Chemical Record, 9, 305-320 (2009).

119. Kinetic Resolution of the Racemic 2-Hydroxyalkanoates Using the Enantioselective Mixed-Anhydride Method with Pivalic Anhydride and a Chiral Acyl-Transfer Catalyst,
Isamu SHIINA, Kenya NAKATA, Keisuke ONO, Masuhiro SUGIMOTO, and Akihiro SEKIGUCHI,
Chemistry - a European Journal, 16, 167-172 (2010).

120. An Effective Kinetic Resolution of Racemic Secondary Benzylic Alcohols Using 3-Pyridinecarboxylic Anhydride and a Chiral Acyl-Transfer Catalyst in the Absence of Tertiary Amine,
Kenya NAKATA and Isamu SHIINA,
Heterocycles, 80, 169-175 (2010).

121. Kinetic Resolution of Racemic a-Arylalkanoic Acids with Achiral Alcohols via the Asymmetric Esterification Using Carboxylic Anhydrides and Acyl-Transfer Catalysts,
Isamu SHIINA, Kenya NAKATA, Keisuke ONO, Yu-suke ONDA, and Makoto ITAGAKI,
Journal of the American Chemical Society, 132, 11629-11641 (2010).

[Highlighted in SYNFACTS 2010, 6(11), 1304 by Prof. Benjamin List and Dr. Ji-Woong Lee]

122. An Effective Kinetic Resolution of Racemic a-Arylpropanoic Acids, a-Arylbutanoic Acids, and b-Substituted-a-arylpropanoic Acids with Bis(9-phenanthryl)methanol as a New Achiral Nucleophile in the Asymmetric Esterification Using Carboxylic Anhydrides and the Acyl-Transfer Catalyst,
Kenya NAKATA, Yu-suke ONDA, Keisuke ONO, and Isamu SHIINA,
Tetrahedron Letters, 51, 5666-5669 (2010).

123. Synthesis of Lasofoxifene, Nafoxidine and Their Positional Isomers via the Novel Three-Component Coupling Reaction,
Kenya NAKATA, Yoshiyuki SANO, and Isamu SHIINA,
Molecules, 15, 6773-6794 (2010).

124. Kinetic Resolution of Racemic 1-Heteroarylalkanols by Asymmetric Esterification Using Diphenylacetic Acid with Pivalic Anhydride and a Chiral Acyl-Transfer Catalyst,
Isamu SHIINA, Keisuke ONO, and Kenya NAKATA,
Chemistry Letters, 40, 147-149 (2011).

125. Kinetic Resolution of the Racemic 1-(Aryloxazol-2-yl)carbinols with Achiral Carboxylic Acids by Asymmetric Esterification: A New Method for the Preparation of Chiral 1,2-Amino Alcohols,
Kenya NAKATA, Keisuke ONO, and Isamu SHIINA,
Heterocycles, 82, 1171-1180 (2011).

126. Various Synthetic Methods Using Aromatic Carboxylic Anhydrides,
Isamu SHIINA,
TCI MAIL Int. Ed. (Contribution as a Research Article), 144, 2-15 (2011).

127. Ridaifen-G Induces Caspase-Independent Atypical Cell Death,
Anniwaer ANLIFEIRE, Manami HATORI, Akinori MORITA, Isamu SHIINA, Kenya NAKATA, Yu-ta TOSAKI, Yanwen WANG, Masahiko IKEKITA, and Guan LI,
Chinese Journal of Cell Biology, 33, 635-644 (2011).

128. (R)-(+)-N-Methylbenzoguanidine ((R)-NMBG) Catalyzed Kinetic Resolution of Racemic Secondary Benzylic Alcohols with Free Carboxylic Acids by Asymmetric Esterification,
Kenya NAKATA and Isamu SHIINA,
Organic & Biomolecular Chemistry, 9, 7092-7096 (2011).

129. A Convenient Method for the Kinetic Resolution of Racemic 2-Hydroxyalkanoates Using Diphenylacetic Anhydride (DPHAA) and Chiral Acyl-transfer Catalyst,
Kenya NAKATA, Akihiro SEKIGUCHI, and Isamu SHIINA,
Tetrahedron: Asymmetry, 22, 1610-1619 (2011).

130. MNBA-Mediated b-Lactone Formation: Mechanistic Studies and Application for the Asymmetric Total Synthesis of Tetrahydrolipstatin,
Isamu SHIINA, Yuma UMEZAKI, Nobutaka KURODA, Takashi IIZUMI, Shunsuke NAGAI, and Takashi KATOH,
J. Org. Chem., 77, 4885-4901 (2012).

[Selected as a Feature Article]

[Highlighted in SYNFACTS 2012, 8(9), 0939 by Prof. Philip Kocienski]

131. A New Method for Production of Chiral 2-Aryl-2-fluorpropanoic Acids Using an Effective Kinetic Resolution of Racemic 2-Aryl-2-fluoropropanic Acids,
Atsushi TENGEIJI and Isamu SHIINA,
Molecules, 17, 7356-7378 (2012).

132. Non-Enzymatic Dynamic Kinetic Resolution of Racemic a-Arylalkanoic Acids: an Advanced Asymmetric Synthesis of Chiral Nonsteroidal Anti-Inflammatory Drugs (NSAIDs),
Isamu SHIINA, Keisuke ONO, and Kenya NAKATA,
Catalysis - Science & Technology, 2, 2200-2205 (2012).

[Selected as a Cover Feature Article]

[Selected as a Hot Article]

[Most Read Article]

133. Kinetic Resolution of Racemic Secondary Benzylic Alcohols by the Enantioselective Esterification Using 3-PCA with Chiral Acyl-transfer Catalysts,
Isamu SHIINA, Kenya NAKATA, Keisuke ONO, and Teruaki MUKAIYAMA,
Helvetica Chimica Acta, 95, 1891-1911 (2012).

134. A New Method for Production of Chiral 2-Aryloxypropanoic Acids Using Effective Kinetic Resolution of Racemic 2-Aryloxycarboxylic Acids,
Atsushi TENGEIJI, Kenya NAKATA, Keisuke ONO, and Isamu SHIINA,
Heterocycles, 86, 1227-1252 (2012).

135. Ridaifen B, a Tamoxifen Derivative, Directly Binds to Grb10 Interacting GYF Protein 2,
Senko TSUKUDA, Tomoe KUSAYANAGI, Eri UMEDA, Chihiro WATANABE, Yu-ta TOSAKI, Shinji KAMISUKI, Toshifumi TAKEUCHI, Yoichi TAKAKUSAGI, Isamu SHIINA, and Fumio SUGAWARA,
Bioorganic & Medicinal Chemistry, 21, 311-320 (2013).

136. Fine Structures in Vibrational Circular Dichroism Spectra of Chiral Molecules with Rotatable Hydroxyl Groups and Their Application in the Analysis of Local Intermolecular Interactions,
Kohzo KONNO, Isamu SHIINA, and Hiroharu YUI,
Journal of Molecular Structure, 30, 260-266 (2013).

137. Total Synthesis of AMF-26, an Antitumor Agent for Inhibition of the Golgi System, Targeting ADP-Ribosylation Factor 1,
Isamu SHIINA, Yuma UMEZAKI, Yoshimi OHASHI, Yuta YAMAZAKI, Shingo DAN, and Takao YAMORI,
Journal of Medicinal Chemistry, 56, 150-159 (2013).

[Selected as a Cover Feature Article]

[Highlighted in ACS News Service Weekly PressPac]

[Most Read Article]

138. Kinetic Resolution of Racemic 2-Hydroxy-g-butyrolactones by Asymmetric Esterification Using Diphenylacetic Acid with Pivalic Anhydride and a Chiral Acyl-Transfer Catalyst,
Kenya NAKATA, Kouya GOTOH, Keisuke ONO, Kengo FUTAMI, and Isamu SHIINA,
Organic Letters, 15, 1170-1173 (2013).

139. Novel Tamoxifen Derivative Ridaifen-B Induces Bcl-2 Independent Autophagy without Estrogen Receptor Involvement,
Yukitoshi NAGAHARA, Midori TAKEYOSHI, Seiya SAKEMOTO, Isamu SHIINA, Kenya NAKATA, Keiko FUJIMORI, Yanwen WANG, Eri UMEDA, Chihiro WATANABE, Shoko UETAKE, Takao YAMORI, Shingo DAN, Yoji YOSHIMI, Takahisa SHINOMIYA, and Masahiko IKEKITA,
Biochemical and Biophysical Research Communications, 435, 657-663 (2013).

140. Search for Novel Anti-tumor Agents from Ridaifens Using JFCR39, a Panel of Human Cancer Cell Lines,
Wen-zhi GUO, Yanwen WANG, Eri UMEDA, Isamu SHIINA, Shingo DAN, and Takao YAMORI,
Biological and Pharmaceutical Bulletin, 36, 1008-1016 (2013).

[Highlighted Paper Selected by Editor-in-Chief]

141. Ridaifen-SB8, a Novel Tamoxifen Derivative, Induces Apoptosis via Reactive Oxygen Species-Dependent Signaling Pathway,
Wen-zhi GUO, Isamu SHIINA, Yanwen WANG, Eri UMEDA, Chihiro WATANABE, Shoko UETAKE, Yoshimi OHASHI, Takao YAMORI, and Shingo DAN,
Biochemical Pharmacology, 86, 1272-1284 (2013).

142. Kinetic Resolution of Racemic a-Hydroxyphosphonates by Asymmetric Esterification Using Achiral Carboxylic Acids with Pivalic Anhydride and a Chiral Acyl-Transfer Catalyst,
Isamu SHIINA, Keisuke ONO, and Takayoshi NAKAHARA,
Chemical Communications, 49, 10700-10702 (2013).

143. An Enantiodivergent Synthesis of (+)- and (-)-Centrolobines via the Asymmetric Esterification Catalyzed by (R)-(+)-N-Methylbenzoguanidine ((R)-NMBG),
Kenya NAKATA, Tatsuya TOKUMARU, Hidetoshi IWAMOTO, Yutaka NISHIGAICHI, and Isamu SHIINA,
Asian Journal of Organic Chemistry, 2, 920-922 (2013).

[Highlighted in ChemistryViews brought by Wiley-VCH & ChemPubSoc Europe]

[Most Accessed Article]

144. Medium-Sized Lactones,
in Natural Lactones and Lactams: Synthesis, Occurrence and Biological Activity (ed T. Janecki),
Isamu SHIINA and Kenya NAKATA,
193-227 (2013), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany.
doi: 10.1002/9783527666911.ch5

145. A Novel Tamoxifen Derivative, Ridaifen-F, Is a Nonpeptidic Small-molecule Proteasome Inhibitor,
Makoto HASEGAWA, Yukari YASUDA, Makoto TANAKA, Kenya NAKATA, Eri UMEDA, Yanwen WANG, Chihiro WATANABE, Shoko UETAKE,Tatsuki KUNOH, Masafumi SHIONYU, Ryuzo SASAKI, Isamu SHIINA, and Tamio MIZUKAMI,
European Journal of Medicinal Chemistry, 71, 290-305 (2014).

146. Asymmetric Mukaiyama Aldol Reactions Using Chiral Diamine-Coordinated Sn(II) Triflate: Development and Application to Natural Product Synthesis,
Isamu SHIINA,
The Chemical Record, 14, 144-183 (2014).

[This paper is dedicated to Professor Teruaki Mukaiyama in celebration of the 40th anniversary of the Mukaiyama aldol reaction.]

147. An Adventurous Synthetic Journey with MNBA from Its Reaction Chemistry to the Total Synthesis of Natural Products,
Isamu SHIINA,
Bull. Chem. Soc. Jpn., 87, 196-233 (2014).

[Award Account; CSJ Award for Creative Work 2013 (FY 2012 in Japan)]

　

continued on TUS HP

for more achievements, see the next site:

http://www.tus.ac.jp/en/fac/p/index.php?19ed